Two sample MR report
ETS2_Conventional Dendritic Cell against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.1495467 | 1.2466393 | 0.9239944 |
| Weighted median | 3 | -0.0988714 | 0.0589350 | 0.0934186 |
| Inverse variance weighted | 3 | -0.1014209 | 0.0483808 | 0.0360553 |
| Simple mode | 3 | -0.0965509 | 0.0662713 | 0.2824585 |
| Weighted mode | 3 | -0.0952512 | 0.0672097 | 0.2921420 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0246755 | 1 | 0.8751784 |
| Inverse variance weighted | 0.0652645 | 2 | 0.9678945 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1081903 | 0.5370122 | 0.8734363 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.43e-05 | 0 | TRUE | 0.4844754 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
